Pharmacology Books Available | Gangaram Jinnah Medical Books

Master the science of drugs and their effects with our extensive selection of Pharmacology Books at Gangaram Jinnah Medical Bookshop. Whether you’re a student, pharmacist, or healthcare professional, these books provide essential insights into drug mechanisms, therapeutic applications, and pharmaceutical advancements. Shop online and enjoy cash on delivery across Pakistan, offered by the best medical bookshop for all your academic and professional needs!

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Conceptual Review Of Pharmacology For NBE 5th Edition
1,200 ₨ – 2,700 ₨
Conceptual Review of Pharmacology for NBE 5th EditionBy Ranjan Kumar Patel (Author)A never before 'Fun and Learn Approach' to study a bland subject like pharmacology. The book retains the same flavor in studying the subject, as the author's classes. The content has been thoroughly revised and updated as per the recent developments. An Integrated Approach of Understanding has been followed in the book with Conceptual Boxes highlighting the Interrelation of Pharmacology with other Clinical and Non-clinical Subjects. Further details related to drugs have been summarized in Clinical Boxes. All chapters now contain Classifications of Various Drug Classes to strengthen the Basic Understanding of the readers. Recent Guidelines in Management of Tuberculosis, Leprosy and HIV have been incorporated. Antimalarial, Anti-leprosy and Anti-HIV Vaccines have also been discussed. A detailed chart on Autonomic Nervous System Drugs has been included for quick revision A never before 'Fun and Learn Approach' to study a bland subject like pharmacology. The book retains the same flavor in studying the subject, as the author's classes. The content has been thoroughly revised and updated as per the recent developments. An Integrated Approach of Understanding has been followed in the book with Conceptual Boxes highlighting the Interrelation of Pharmacology with other Clinical and Non-clinical Subjects. Further details related to drugs have been summarized in Clinical Boxes. All chapters now contain Classifications of Various Drug Classes to strengthen the Basic Understanding of the readers. Recent Guidelines in Management of Tuberculosis, Leprosy and HIV have been incorporated. Antimalarial, Anti-leprosy and Anti-HIV Vaccines have also been discussed. A detailed chart on Autonomic Nervous System Drugs has been included for quick revision

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Targets of Cancer Diagnosis and Treatment: Ion Transport in Tumor Biology (Reviews of Physiology, Biochemistry and Pharmacology Book 183)
500 ₨ – 1,050 ₨
Targets of Cancer Diagnosis and Treatment: Ion Transport in Tumor Biology (Reviews of Physiology, Biochemistry and Pharmacology Book 183)By Christian Stock (Editor), Luis A. Pardo (Editor)This third and final volume in the "Ion Transport in Tumor Biology" collection presents novel diagnostic and therapeutic approaches in cancer based on the exploitation of ion transport proteins. The authors critically examine several transportome members, particularly Na⁺, K⁺, Ca²⁺, and Cl^- channels, as well as organic solute carriers regarding their suitability as therapeutic targets. Synergistic effects resulting from the combined use of classical cytostatics with ion transport-inhibiting drugs are pointed out, and the capability of bispecific antibodies to function as anticancer drugs is discussed.As readers will also learn, the use of ion channel inhibitors could improve the outcome of radiotherapy because the development of radio-resistance during radiotherapeutic treatment often correlates with increases in the expression levels and conductance of ion channels. The translational topics of this volume form a bridge between biochemical research and therapeutic application. As part of a three-volume collection, this book will fascinate members of the active research community, as well as clinicians in the cancer field.

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Pharmacology and the Nursing Process 10th Edition
1,500 ₨ – 3,450 ₨
Pharmacology and the Nursing Process 10th EditionBy Linda Lane Lilley RN PhD, Shelly Rainforth Collins PharmD BCGP, Julie S. Snyder MSN RN MEDSURG-BCGain the pharmacology knowledge and skills you need to administer medications safely! Pharmacology and the Nursing Process, 10th Edition provides practical, easy-to-use pharmacology information, emphasizing the application of the nursing process and prioritization throughout the book. Coverage begins with pharmacology basics, then discusses drugs by body systems and drug functions. Hundreds of full-color illustrations show how drugs work in the body and depict key steps in medication administration. Written by pharmacology experts Linda Lane Lilley, Shelly Rainforth Collins, and Julie S. Snyder, this bestselling textbook makes it easy to understand and apply pharmacology concepts and provide safe, quality nursing care.
Focus on need-to-know information includes discussions of what nurses may encounter during drug administration in a variety of health care settings, providing accounts of real-life medication errors and tips for avoiding those errors.
The Nursing Process is applied to each category of drugs, ensuring that you administer medications accurately and safely, and includes the steps of assessment, human need statements, planning, implementation, and evaluation.
Emphasis on drug classes describes key similarities and differences among the drugs in each class, making it easier to understand how individual drugs work in the body.
Consistent presentation for each drug group includes the mechanism of action, indications, contraindications, adverse effects, interactions, and dosages, concluding with drug profiles of individual drugs in the class or group.
High-alert icons identify medications that pose a greater risk to patient safety.
Focus on prioritization includes prioritized nursing diagnoses along with a corresponding prioritization of goals and outcomes, to help you learn to connect nursing diagnoses with goals and outcomes.
Ease of readability makes difficult content more understandable.
Photo atlas features more than 100 drawings and photographs showing drug administration techniques.
Dosages tables summarize generic and trade names, pharmacologic class, normal dosage ranges, and indications for the drugs.
Learning features at the beginning of each chapter include objectives and key terms, and at the end of each chapter, key points, critical thinking questions, review questions, and a list of resources available on the Evolve website.
QSEN coverage includes the use of human need theory with human need statements, case studies featuring collaboration and teamwork content, Preventing Medication Errors boxes, and a discussion of the QSEN initiative as it relates to the safety and quality of patient care.
NEW! Updated drug content reflects the latest FDA drug approvals, withdrawals, and therapeutic uses, and includes updated nursing content.

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Fundamentals of Pharmacology for Paramedics
600 ₨ – 1,350 ₨
Fundamentals of Pharmacology for ParamedicsBy Ian Peate (Editor), Suzanne Evans (Editor), Lisa Clegg (Editor)Fundamentals of Pharmacology for Paramedics provides students with the insight and understanding of pharmacological essentials needed to respond effectively to the patients' needs. This textbook will help students improve, expand, and enhance their expertise and the overall health and wellbeing of their patients, while boosting their self-confidence as paramedics in the process. This textbook integrates the extensive knowledge of pharmacology into a workable and accessible plan of care that will help to improve patient care. The book also includes:
Thorough introductions to pharmacology and how to use pharmaceutical, and prescribing reference guides
Comprehensive explorations of the legal and ethical issues of pharmacology within paramedicine and the role of the paramedic in medicines management
Practical discussions of pharmacodynamics, pharmacokinetics, drug formulations, and adverse drug reactions
In-depth examinations of a wide variety of medicines, including analgesics, antibacterials, and medications used in the cardiovascular, renal, respiratory, gastrointestinal, and nervous systems
Written for students of paramedicine, Fundamentals of Pharmacology for Paramedics would also prove an indispensable resource for practicing paramedics seeking a practical, one-stop reference on a challenging subject.

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Comprehensive Pharmacology by Terry P. Kenakin
7,950 ₨ – 18,100 ₨
Comprehensive PharmacologyBy Terry P. Kenakin PhD (Editor)Comprehensive Pharmacology, Seven Volume Set is organized into twelve sections that explore therapeutic areas, with a total of 320 comprehensive articles and 6,800 pages of important findings. Sections contain highly detailed coverage of information that has been overseen by an editorial board made up of well-respected, field leading experts. The content in this book offers readers an in-depth and easily accessible reference work on every aspect of pharmacological research surrounding the pharmacology of all therapeutic applications of drugs, their mechanism of action and their therapeutic values.These elements are essential as drugs are almost never tested and developed in the actual therapeutic system, but rather in test systems from which parameters must be determined to predict activity in systems of varying ambient physiology. As different technologies rapidly evolve, there is an ever-increasing level of knowledge about the pharmacology of known drugs, along with increasing capability to utilize pharmacological systems to predict new drug activity, all of which must be communicated to professionals in varying fields.
Contains chapters that follow a consistent and templated approach, resulting in well-structured content that enhances user experience and appeal
Offers a comprehensive review on a wealth of information on pharmacology and how it utilizes concepts and techniques from a broad array of sciences, ranging from chemistry to physiology to medicine
Includes a wider use of color and multimedia content, with interactive features, links, computational modeling and animations to illustrate the effects of toxic substances in various contexts

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Forskolin: Natural Sources, Pharmacology and Biotechnology
350 ₨ – 750 ₨
Forskolin: Natural Sources, Pharmacology and BiotechnologyBy T. Pullaiah (Author)This monograph compiles updated information about forskolin, a labdane diterpene that is produced by the Coleus plant. Forskolin has a large number of practical uses and the book delves into the various aspects of this chemical. It includes topics such as the botanical source of forskolin and the cultivation of Coleus forskohlii, source. It also covers the biosynthetic pathways in natural sources and also through different biotechnological applications. Chapters include the potential and products in the Forskolin market. The book also covers the methods for enhanced production of forskolin from natural sources and through tissue culture methods for improvement of the plant for higher content of forskolin. It discusses the role of endophytes in the production of forskolin.The book is useful for students and researchers in the field of botany, pharmacology and biochemistry. It also serves scientists in various pharmaceutical industries.

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Clinical Pharmacology During Pregnancy 2nd Edition
850 ₨ – 1,850 ₨
Clinical Pharmacology During Pregnancy 2nd EditionBy Donald Mattison (Editor), Lee-Ann Halbert (Editor)Clinical Pharmacology During Pregnancy, Second Edition is written for clinicians, physicians, midwives, nurses, pharmacists and other medical professionals involved in the care of women during pregnancy. The book focuses on the impact of pregnancy on drug disposition and includes coverage of treatments for diseases of specific body systems as well as essential content on dosing and efficacy. This update includes substantially expanded sections on the ethics of pharmacological research in pregnancy and physiologic changes, along with new sections on patient reported outcomes in pregnancy, delivery and postnatal care, and the use of pharmacokinetic and pharmacodynamic approaches to estimate maternal, placental and fetal dosing.The broad range of this book encompasses analgesics, antiasthmatics, antidepressants, heart and circulatory drugs, vitamins and herbal supplements, and more. Topics in chemotherapy and substance abuse are also covered, as are research issues, including clinical trial design and ethical considerations.
Uses an evidence-based approach for therapeutics during pregnancy
Presents a summary of specific medications by indication, including up-to-date information on dosing and efficacy in pregnancy for the given indication
Includes significant new sections on physiologic changes and the ethics of pharmacological research in pregnancy

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Bioactives and Pharmacology of Medicinal Plants: Volume 1
800 ₨ – 1,750 ₨
Bioactives and Pharmacology of Medicinal Plants: Volume 1By T. Pullaiah (Editor)This two-volume book presents an abundance of important information on the bioactive and pharmacological properties of medicinal plants. It provides valuable comprehensive research and studies on bioactive phytocompounds of over 68 important medicinal plants with beneficial properties. For each species included in the volume, a brief introduction is given along with their bioactive compounds and chemical structures, followed by their chief pharmacological activities that include antiviral, antimicrobial, antioxidant, anti-cancer, anti-inflammatory, antidiabetic, hepatoprotective, nephroprotective, and cardioprotective activities. A review of the published literature on pharmacological activities of each species is included also, providing a thorough resource on each of the plants covered in the volume.The book’s editor, an acknowledged expert in this area, foresees that these volumes will become a reliable standard resource for the development of new drugs. The volumes will be a valuable addition to the libraries of pharmacy institutes and pharmacy professors, research scholars, and postgraduate students of pharmacy and medicine, and enlightened medical professionals and pharmacists, phytochemists, and botanists will find much of value as well.

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Handbook of Basic and Clinical Ocular Pharmacology and Therapeutics
1,050 ₨ – 2,400 ₨
Handbook of Basic and Clinical Ocular Pharmacology and TherapeuticsBy Sunny Ohia (Editor), Najam Sharif (Editor)Handbook of Basic and Clinical Ocular Pharmacology and Therapeutics provides a review of the basic anatomy, physiology, biochemistry and pathology of the eye with a focus drug therapy, drug delivery and use of therapeutic medical miniature devices. An understanding of the pharmacological actions of drugs acting on the eye requires the student and health care practitioner to learn additional principles in basic and clinical sciences that are unique to this organ. As a sensory organ, the eye is relatively inaccessible to the systemic circulation due to the blood-vitreous, blood-aqueous and blood-retinal barriers. Consequently, the administration of drugs for therapeutic effects in the eye necessitates an understanding of physico-chemical properties of the molecules and pharmacokinetic principles involved in the access to its site of action via topical, intracameral and intravitreal administration. This book includes information on the general principles of pharmacokinetics and pharmacodynamics of drugs as it pertains to the eye and in combating ocular disorders and diseases. Using a disease-themed approach, the book discusses basic and clinical pharmacological principles involved in the therapy of these diseases including the ocular side effect of systemically-administered drugs, drugs used in ophthalmic surgery and miscellaneous agents, the therapeutic utility of biologics, drug conjugates, combination products, gene and cellular therapy are also covered. Handbook of Basic and Clinical Ocular Pharmacology and Therapeutics is useful as a primary and secondary source of reference for up-to-date information about the pharmacological mechanisms of action, pharmacokinetics, side effects, drug-drug interactions and therapeutic indications of drugs for pharmacologists, pharmaceutical scientists, students in the health care disciplines (nursing, pharmacy, optometry, medical), and practitioners in optometry and ophthalmology.
Explains the mechanisms of action, side-effects and therapeutic uses of drugs, biologics, miniature devices, gene and cellular therapies for the eye
Provides a comprehensive review of the anatomy, physiology, biochemistry, pharmacology, microbiology, genetics and pathology of parts of the eye involved in drug therapy to combat eye disorders and diseases
Explores the pharmacological and clinical basis of drugs, drug conjugates, combination products used in the treatment of anterior and posterior segment diseases

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Medical Pharmacology and Therapeutics 6th Edition
1,200 ₨ – 2,700 ₨
Medical Pharmacology and Therapeutics 6th EditionBy Derek G. Waller, Andrew W. Hitchings, Anthony P. SampsonMedical Pharmacology & Therapeutics provides all the information medical and healthcare students need throughout their degree programme and beyond, including for professional qualifications such as the PSA.This all-round textbook covers basic pharmacology through to drug prescribing in clinical contexts, covering the pathogenic mechanisms of disease; drug actions, side effects, and the therapeutic principles of drug use. It takes a helpful systems-based approach that orders information according to body systems and disease areas, rather than by drug class.Now in its sixth edition, the book has been fully updated to include latest scientific understanding of drug action and administration and current best practice in prescribing medications, informed by the latest national guidelines.
A clinical focus throughout – suitable for medical, nursing and other healthcare students throughout their training
Thorough update of clinically-relevant medicines to ensure best practice
Expanded discussion of the pathophysiology and management of shockRevised discussion of the management of chronic painInformation aligned with the British National Formulary (BNF), NICE guidelines and relevant professional benchmarks
Comprehensive drug compendia allow all drugs to be identified and placed within their respective classes
Extensive self-assessment questions to support learning and revision
New to this edition Expanded discussion of the pathophysiology and management of shock
Revised discussion of the management of chronic pain
Consideration of treatment of Covid-19

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Toll-like Receptors in Health and Disease (Handbook of Experimental Pharmacology 276)
550 ₨ – 1,150 ₨
Toll-like Receptors in Health and Disease (Handbook of Experimental Pharmacology 276)By Vijay Kumar (Editor)The current book is focussed on the Toll-like receptors (TLRs), which are the first pattern recognition receptors (PRRs) discovered in humans. For example, TLR4 was first recognized in humans in 1997 as a PRR recognizing the Gram-negative bacterial lipopolysaccharide (LPS). This discovery revolutionized the field of innate immunity and filled the long-standing gap in the pathogen recognition by the immune system. Now, it is well established that humans have 10 (TLR1-TLR10) and mice have 12 (TLR1-TLR13) functional TLRs, excluding TLR10 that is present as a defective pseudogene. TLRs are present as both membrane-bound extracellular (TLR1, TLR2, TLR4, TLR5, TLR6, and TLR10) and intracellular (TLR3, TLR7, TLR8, and TLR9) PRRs in humans, which identify different pathogen or microbe-associated molecular patterns (PAMPs or MAMPs) and death or damage-associated molecular patterns (DAMPs) released by the host cells. A lot of development in the TLR biology has occurred in last 24 years since there first discovery in humans.The book is intended to describe their role in the host defence, human reproduction, non-infectious sterile inflammatory conditions, including brain immunity and cerebrovascular diseases, signaling mechanisms, adaptive immunity, and their targeting for drug development.

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Antidiabetic Plants for Drug Discovery: Pharmacology, Secondary Metabolite Profiling, and Ingredients with Insulin Mimetic Activity
600 ₨ – 1,250 ₨
Antidiabetic Plants for Drug Discovery: Pharmacology, Secondary Metabolite Profiling, and Ingredients with Insulin Mimetic ActivityBy Deepu Pandita (Editor), Anu Pandita (Editor), Chander Bhanu (Editor)This volume takes an in-depth look at the potential pharmacological applications of 11 important antidiabetic plants, examining their antihyperglycemic, hypoglycemic, and anti-lipidemic properties along with current genome editing research perspectives.Plant natural products, or phytoconstituents, are promising candidates for antidiabetic pharmacological actions. The phytoconstituents, such as ï¬‚ avonoids, terpenoids, saponins, carotenoids, alkaloids and glycosides, play vital roles in the current and future potent antidiabetic drug development programsEach chapter reviews a particular plant with antidiabetic properties, explaining the therapeutic aspects, its active antidiabetic compounds, and relevant genome editing technology. The specific plants discussed include Azadirachta indica (commonly known as neem, nimtree or Indian lilac), Gymnema sylvestre (commonly called gymnema, Australian cowplant, and Periploca of the woods), Syzygium cumini (commonly known as Malabar plum, Java plum, black plum, jamun or jambolana), Ceylon cinnamon (or true cinnamon, as opposed to cassia cinnamon), insulin plant (or Costus pictus), Trigonella foenum-graecum (better known as fenugreek), Mulberry, Nigella sativa L. (black caraway, also known as black cumin, nigella, kalojeera, kalonji or kalanji), Aegle marmelos (L.) (commonly known as bael (or bili or bhel), also Bengal quince, golden apple, Japanese bitter orange, stone apple or wood apple), Ficus benghalensis (the banyan, banyan fig and Indian banyan), and of course, garlic (Allium sativum).Antidiabetic Plants for Drug Discovery: Pharmacology, Secondary Metabolite Profiling, and Ingredients with Insulin Mimetic Activity will serve as a valuable source of information for students, drug researchers, medical practitioners, diabetic patients, and many others in the effort to gain understand of how these plant drug molecules can help fight diabetes.

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Introduction to Basics of Pharmacology and Toxicology: Volume 3 : Experimental Pharmacology : Research Methodology and Biostatistics (Introduction to Basics of Pharmacology and Toxicology, 3)
1,400 ₨ – 3,200 ₨
Introduction to Basics of Pharmacology and Toxicology: Volume 3: Experimental Pharmacology: Research Methodology and BiostatisticsBy Mageshwaran Lakshmanan (Editor), Deepak Gopal Shewade (Editor), Gerard Marshall Raj (Editor)This volume is designed to impart the fundamental concepts in experimental pharmacology, research methodology and biostatistics. Through this book, the readers will learn about different methods involved in drug discovery, experimental animals and their care, equipments and the various bioassays used in experimental pharmacology. This book contains special sections on various drug screening methods involved in the evaluation of different body systems. Certain sections provide the healthcare professionals with the knowledge necessary to interpret clinical research articles, design clinical studies, and learn essential concepts in biostatistics in an expedient and concise manner. Basic principles and applications of simple analytical methods employed in drug analysis are well written under one section.It focuses on the basic and advanced laboratory techniques and also on computer simulated data, written extensively under the Biostatistics section. The methods used for drug analysis have been described in adequate detail with cross-references for further studies and comprehension. Overall, the book is designed systematically with four broad sections with extensive subdivisions for easy tracking, interpretation, and understanding.

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Methods for Novel Psychoactive Substance Analysis (Methods in Pharmacology and Toxicology)
500 ₨ – 1,050 ₨
Methods for Novel Psychoactive Substance AnalysisBy Marta Concheiro (Editor), Karl B. Scheidweiler (Editor)This collection provides detailed information on current advances in analytical methods and strategies employed for monitoring and discovering a wide range of novel psychoactive substances (NPS) in clinical and forensic laboratories. The main classes of NPS in terms of prevalence include synthetic cannabinoids, synthetic cathinones, synthetic opioids, and designer or synthetic benzodiazepines, and this book explores selecting the appropriate sample matrix and analytical testing approaches for laboratories faced with NPS drug testing, such as in blood, urine, saliva, and hair. Written for the Methods in Pharmacology and Toxicology series, chapters in this volume feature the kind of detailed implementation advice from the experts that leads to successful results in the lab.Authoritative and practical, Methods for Novel Psychoactive Substance Analysis serves as an ideal guide for forensic and clinical toxicologists, pharmacologists and chemists inacademic and research settings, as well as for private laboratories seeking to increase our ability to test for these substances.

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Opioids: Pharmacology, Abuse, and Addiction
650 ₨ – 1,400 ₨
Opioids: Pharmacology, Abuse, and AddictionBy Silvia L. Cruz (Editor)Opioids are responsible for the vast majority of preventable deaths related to drug use, and opioid crisis is a serious international health problem. Opioids are also the mainstay in pain treatment and are invaluable tools in palliative care. The purpose of this book is to present an overview of the complex field of opioid pharmacology through evidence-based chapters in clear language backed up with sound scientific evidence, providing researchers and health professionals with a firm understanding of their effects and mechanisms of action. The authors present an overview of the history of opioids from ancient civilizations to the current opioid crisis, covering state-of-the-art advances on opioid-induced signal transduction, opioids in pain management, and the neuroinflammatory effects of opioids. Also discussed are opioid use disorders and their treatment. The authors also review the growing body of evidence of opioid effects on innate and adaptive immune responses, discussing the molecules involved in the crosstalk between opioids and innate immunity receptors to provide an updated view of those compounds as important regulators of inflammation and host defense against pathogens and damage. The overall purpose is to provide the reader with a deeper knowledge of this field despite the complexities associated with the existence of numerous ligands, receptor subtypes, and complex pharmacological profiles. To this end, the chapter authors arespecialists in the field who also have extensive experience in teaching, hoping to lend their expertise in translating complex concepts into comprehensive and clear explanations.

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How Synthetic Drugs Work: Insights into Molecular Pharmacology of Classic and New Pharmaceuticals
950 ₨ – 2,100 ₨
How Synthetic Drugs Work: Insights into Molecular Pharmacology of Classic and New PharmaceuticalsBy Imran Kazmi (Editor), Sanmoy Karmakar (Editor), Md Adil Shaharyar (Editor), Muhammad Afzal (Editor), Fahad A. Al-Abbasi (Editor)How Synthetic Drugs Work: Insights into Molecular Pharmacology of Classic and New Pharmaceuticals provides comprehensive, structured access to robust information on molecular pharmacology for clinicians, research scientists and advanced health care students. The book covers the foundations of molecular pharmacology and the main drug classes, including detailed information on their mechanisms of action and the application of molecular pharmacology in drug development. This book is an ideal reference for graduate students and researchers in pharmacology, however, researchers in corporate settings will also benefit from the book's structured and detailed coverage of mechanisms of action of synthetic drugs.
Presents the mechanism of action of most recent synthetic drugs available
Includes newly reported action mechanisms of conventional drugs
Contains colored illustrations of the pathway through which the drug exerts therapeutic action

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The Pharmacology of Taste (Handbook of Experimental Pharmacology 275)
600 ₨ – 1,300 ₨
The Pharmacology of Taste (Handbook of Experimental Pharmacology, Volume 275)By R. Kyle Palmer (Editor), Guy Servant (Editor)The Pharmacology of Taste is comprised of contributions by leading scientists from the field of chemosensory research, presented all together in the context of pharmacological principles of receptor function. The chapters cover all levels of scientific inquiry, from molecular and physiological mechanisms underlying taste signaling to its manifestation in overt behavior. The overarching objective of this volume is to inspire the application of concepts and methods of pharmacology to the study of the chemosenses.

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Physiology, Pharmacology and Pathology of the Blood-Brain Barrier (Handbook of Experimental Pharmacology, 273)
600 ₨ – 1,300 ₨
Physiology, Pharmacology and Pathology of the Blood-Brain Barrier (Handbook of Experimental Pharmacology, Volume 273)By Zameel Cader (Editor), Winfried Neuhaus (Editor)This book presents a comprehensive collection of current knowledge and leading research about the blood-brain barrier. The chapters are organized in four main parts providing basic information and novel insights about the physiology of the blood-brain barrier, the challenges related to finding and developing drugs crossing the blood-brain barrier, experimental methods to study the blood-brain barrier and the role of the blood-brain barrier in disease mechanisms and its consequences for drug development. In the first part the readers will discover the structure, function and developmental aspects of the blood-brain barrier and gain novel insights into the complexity and functionality of the neurovascular unit and energy metabolism of brain endothelial cells. Chapters of the second part focus on translational challenges from the bench to the bedside in CNS drug development, shed light on the importance to understand the brain distribution of drugs related to their efficacy, elaborate on general pharmacokinetic considerations for CNS drugs and introduce current and novel drug delivery strategies to overcome the blood-brain barrier. The experimental part of the book covers mathematical and in vitro models as well as animal and human methods in blood-brain barrier research. Specific emphasis is set on the description of the methods, the role of species differences for data interpretation, novel human models based on stem cells with the potential for personalized medicine and technical considerations and tips helpful for readers interested in working with these models. In the fourth part particular attentions is given to the blood-brain barrier, its changes and participation during disease progression. Chapters summarize alterations of the blood-brain barrier that are present in common disorders such as Alzheimer’s disease, multiple sclerosis, stroke, traumatic brain injury, epilepsy and brain tumors. Present therapies will be discussed and the consequences for novel treatment approaches that need to bypass the blood-brain-barrier will be explored. In addition, experts discuss the question in how far changes at the blood-brain barrier are causally linked to disease progressions and consequently could serve as therapeutic targets. This collection is designed to appeal to a wide readership from students through basic and applied scientist to pharmacologists, medical doctors and stakeholders from the pharmaceutical industry and regulatory affairs. Due its comprehensive content the book has the potential to become a standard work in the field of blood-brain barrier research.

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Pharmacology of Immunosuppression (Handbook of Experimental Pharmacology 272)
600 ₨ – 1,300 ₨
Pharmacology of Immunosuppression(Handbook of Experimental Pharmacology, Volume 272)By Howard J. Eisen (Editor)The goal of this book is to provide a guide and detailed review of immunosuppression in terms of molecular mechanisms of action, side effects and clinical trials that validated their utility. This includes their use in solid organ transplantation, bone marrow transplantation and autoimmune diseases and inflammatory diseases. This book is a critical review of these topics and a vital resource.

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In Situ Bioavailability and Toxicity of Organic Chemicals in Aquatic Systems (Methods in Pharmacology and Toxicology)
500 ₨ – 1,100 ₨
In Situ Bioavailability and Toxicity of Organic Chemicals in Aquatic Systems (Methods in Pharmacology and Toxicology)By Thomas-Benjamin Seiler (Editor), Markus Brinkmann (Editor)This detailed volume examines the complex study of the assessment of in situ bioavailability and toxicity of organic chemicals in aquatic systems with a toolbox of reliable techniques. Beginning with a section on approaches for chemical analytical and bioanalytical techniques in bioavailability research, the book continues with methods to monitor effects in situ and conduct bioassays to assess the effects of complex environmental samples. It concludes with descriptions of various computational models. Written for the Methods in Pharmacology and Toxicology series, chapters feature the kind of expert implementation advice that leads to greater success in the field. Authoritative and versatile, In Situ Bioavailability and Toxicity of Organic Chemicals in Aquatic Systems serves as an ideal guide to aid in tackling the challenge of analyzing and understanding chemical pollution in aquatic systems.

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