This contributed volume offers a comprehensive discussion on how to design and discover pharmaceuticals using computational modeling techniques. The different chapters deal with the classical and most advanced techniques, theories, protocols, databases, and tools employed in computer-aided drug design (CADD) covering diverse therapeutic classes. Multiple components of Structure-Based Drug Discovery (SBDD) along with its workflow and associated challenges are presented while potential leads for Alzheimer’s disease (AD), antiviral agents, anti-human immunodeficiency virus (HIV) drugs, and leads for Severe Fever with Thrombocytopenia Syndrome Virus (SFTSV) disease are discussed in detail. Computational toxicological aspects in drug design and discovery, screening adverse effects, and existing or future in silico tools are highlighted, while a novel in silico tool, RASAR, which can be a major technique for small to big datasets when not much experimental data are present, is presented. The book also introduces the reader to the major drug databases covering drug molecules, chemicals, therapeutic targets, metabolomics, and peptides, which are great resources for drug discovery employing drug repurposing, high throughput, and virtual screening. This volume is a great tool for graduates, researchers, academics, and industrial scientists working in the fields of cheminformatics, bioinformatics, computational biology, and chemistry.
Curriculum Development for Medical Education: A Six-Step Approach third edition
by Patricia A. Thomas (Editor), David E. Kern (Editor), Mark T. Hughes (Editor), Belinda Y. Chen (Editor)
The third edition of this invaluable text reflects significant changes driving curriculum development and renewal throughout medical education.
Based on a proven six-step model and including examples and questions to guide application of those timeless principles, Curriculum Development for Medical Education is a practical guidebook for all faculty members and administrators responsible for the educational experiences of medical students, residents, fellows, and clinical practitioners.
Incorporating revisions driven by calls for reform and innovations in medical education that challenge established teaching models, the third edition includes an awareness of new accreditation standards and regulatory guidelines. The authors have expanded their discussion of survey methodology for needs assessment and stress the importance of writing competency-based goals and objectives that incorporate milestones, entrustable professional activities, and observable practice activities. With updated examples focusing on interprofessional education, collaborative practice, and educational technology, they describe educational strategies that incorporate the new science of learning. A completely new chapter presents the unique challenges of curriculum development for large, long, and integrated curricula.
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Curriculum Development for Medical Education: A Six-Step Approach fourth edition
by Patricia A. Thomas (Editor), David E. Kern (Editor), Mark T. Hughes (Editor), Sean A. Tackett (Editor), Belinda Y. Chen (Editor)
A thoroughly revised and updated fourth edition of a text that has become an international standard for curriculum development in health professional education.
Intended for faculty and other content experts who have an interest or responsibility as educators in their discipline, Curriculum Development for Medical Education has extended its vision to better serve a diverse professional and international audience. Building on the time-honored, practical, and user-friendly approach of the six-step model of curriculum development, this edition is richly detailed, with numerous examples of innovations that challenge traditional teaching models. In addition, the fourth edition presents
• updates in our understanding of how humans learn; • a new chapter on curricula that address community needs and health equity; and • an increased emphasis throughout on health systems science, population health, equity, educational technology in health professions education, and interprofessional education.
This new edition remains a cutting-edge tool and practical guidebook for faculty members and administrators responsible for the educational experiences of health professional students, residents, fellows, and practitioners. It includes chapters on each of the steps of curriculum development, with updated examples and questions to guide the application of the timeless principles. Subsequent chapters cover curriculum maintenance and enhancement, dissemination, and curriculum development for larger programs. Appendixes present examples of full curricula designed using the six-step approach, which is widely recognized as the current standard for publication and dissemination of new curricula and provides a basis for meaningful educational interventions, scholarship, and career advancement for the health professional educator. The book also provides curricular, faculty development, and funding resources.
Contributors: Chadia N. Abras, Belinda Y. Chen, Heidi L. Gullett, Mark T. Hughes, David E. Kern, Brenessa M. Lindeman, Pamela A. Lipsett, Mary L. O'Connor Leppert, Amit K. Pahwa, Deanna Saylor, Mamta K. Singh, Sean A. Tackett, Patricia A. Thomas
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- Current Understanding And New Techniques In Refractive SurgeryBy Michael O'Keefe (Editor)In This Book, We Examine The Current Techniques Of Refractive Surgery, And Lesser-Known Areas, And We Describe Some Of The Newer Techniques. Our Intention Is To Reinforce Our Understanding Of The Basic Areas Of LASEK, LASIK, Dry Eye, Topography And Aberrations. We Have Added New And Controversial Areas Of Research Such As Refractive Surgery To Patients With Strabismus And Paediatric Refractive Surgery And Have Highlighted The Current Understanding Of Ectasia And Its Management. Although Refractive Surgery Is Popular With Up To A 20 Year Follow Up, Little Is Known About The Risk Of Recurring Refractive Errors. We Discuss This In Detail And Give Our Own Follow-Up Outcomes. Many Regard The Frontier As Presbyopia, But As It Is A Moving Target, We Still Lack The Information To Decide Whether The Future Will Be Cornea Or Lens. We Discuss The Current Corneal Techniques Such As Inlays And Supracor, Their Advantages And Disadvantages. Our Target Readers Are Ophthalmologists In Training As Well As Those Who Practice Refractive Surgery.You can buy this product at Gangaram Jinnah Medical Books Shop for home delivery and Cash on delivery to all over Pakistan. All kind of medical books are available.
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Current Trends in Cardiovascular Research
by Jan Fedacko (Editor), Krasimira Hristova (Editor), Germaine Cornelissen (Editor), Ram B. Singh (Editor)
Current Trends in Cardiovascular Research brings evidence to the medical community about the role of metabolic factors in the pathogenesis of cardiovascular function and dysfunction which results in different cardiovascular diseases.
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Current Therapy of Trauma and Surgical Critical Care 3rd Edition
by Juan A. Asensio MD FACS FCCM FRCS KM (Editor), Wayne J. Meredith (Editor)
Drawing on the experience and knowledge of master world-renowned trauma surgeons, Current Therapy of Trauma and Surgical Critical Care, 3rd Edition, offers a comprehensive summary of optimal treatment and post-operative management of traumatic injuries. Ideally suited for everyday use, this practical, concise reference highlights the most important aspects of urgent surgical care, from damage control to noninvasive techniques to chemical and biological injuries. A focus on the surgical techniques required to manage even the most complex injuries makes it both an excellent resource for quick review before entering the operating room and a valuable review tool for board certification or recertification. Covers the entire spectrum of Trauma Surgery and Surgical Critical Care―from initial evaluation, military and civilian field and trauma center evaluation and resuscitation, to diagnosis, operative, and postoperative critical care and outcomes―in nearly 100 print and 39 online-exclusive chapters, all newly streamlined to emphasize frontline procedural treatment.
Features extensive new data and updates to Cardiac, Thoracic, Vascular, and Military Surgery chapters, plus numerous new intraoperative photographs and high-quality line drawings that highlight the most important aspects of urgent surgical care.
Contains 14 new chapters, including Innovations in Trauma Surgery Simulation; Air Evacuation and Critical Care in Military Casualties; REBOA: Indications and Controversies; Penetrating Extracranial Vertebral Artery; Penetrating Arterio-Venous Fistulas; The Genomics of Profound Shock and Trauma; ECMO; and newer strategies, such as nerve blocks for pain management to combat the opioid epidemic.
Incorporates a wealth of military knowledge from both recent and past military conflicts, as well as from asymmetric warfare; many of the authors and co-authors have extensive past and present military experience.
Uses a consistent, easy-to-follow chapter format throughout, for quick and easy reference and review.
Reviews the essential principles of diagnosis and treatment, as well as the specifics of surgical therapy, making it useful for surgeons across all specialties.
Integrates evidence-based practice guidelines into the text whenever possible, as well as comprehensive utilization of the American Association for the Surgery of Trauma – Organ Injury Scales (AAST-OIS).
Contains such a wealth of operative photographs and line drawings, both in the printed version and many more in the electronic version, that it could be considered an Atlas of Trauma Surgery.
An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud.
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Current Surgical Therapy 12th Edition
by Andrew M. Cameron MD PhD FACS (Editor)
For more than 30 years, Current Surgical Therapy has been the go-to resource for both residents and practitioners for expert advice on today’s best treatment and management options for general surgery. The 12th Edition, by Drs. John L. Cameron and Andrew M. Cameron, remains the ideal reference for written, oral, and recertifying board study, as well as for everyday clinical practice. Twelve brand-new chapters and many new contributing authors keep you up to date with recent changes in this fast-moving field, helping you achieve better outcomes and ensure faster recovery times for your patients.
Presents practical, hands-on advice on selecting and implementing the latest surgical approaches from today’s preeminent general surgeons. Approaches each topic using the same easy-to-follow format: disease presentation, pathophysiology, and diagnostics, followed by surgical therapy. Discusses which approach to take, how to avoid or minimize complications, and what outcomes to expect. Helps you visualize how to proceed with full color images throughout. Trusted by generations of general surgeons as the definitive source on the most current surgical approaches, providing a quick, efficient review prior to surgery and when preparing for surgical boards and ABSITEs. Expert Consult™ eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices. Features nearly 300 succinct, well-illustrated chapters that summarize today’s best treatment and management advice for a wide variety of diseases and associated surgeries. Includes twelve brand-new chapters covering islet allotransplantation; lower extremity amputations; prehospital management of the trauma patient; ERAS: colon surgery; minimally invasive pancreatic surgery; five new chapters on the breast, and more.
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- Sale!This book is a collection of full papers based on the peer-reviewed submissions accepted for the ERIDOB 2020 conference (which was cancelled due to COVID-19). ERIDOB brings together researchers in Biology Education from around the world to share and discuss their research work and results. It is the only major international conference on biology education research, and all the papers therefore are written by international researchers from across Europe (and beyond), which present the findings from a range of contemporary biology education research projects. They are all entirely new papers describing new research in the field. The papers are peer-reviewed by experienced international researchers selected by the ERIDOB Academic Committee. The papers reflect the ERIDOB conference strands by covering topics on:
- Socioscientific issues, Nature of Science and scientific thinking
- Teaching and learning in biology
- Perceptions of biology and biology education
- Textbook analysis
- Outdoor and environmental education